Open Access

Fig. 1


Download original image

Generic electrostatic model of calcium/sodium ion channel [11]. The model describes the channel's selectivity filter as an axisymmetric, water-filled pore of radius R = 0.3 nm and length L = 1.6 nm through a protein hub embedded in the cellular membrane. A centrally placed, uniform, rigid ring of negative charge Qf is embedded in the wall to represent the charged residues of real Ca2+/Na+ channels. We take both the water and the protein to be homogeneous continua describable by relative permittivities and εp = 2, respectively, together with an implicit model of ion hydration whose validity is discussed elsewhere. The moving monovalent Na+ and divalent Ca2+ ions are assumed to obey self-consistently both Poisson's electrostatic equation and the Langevin equation of motion.

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.