Open Access

Fig. 5


Download original image

Permeability to Na+ and Ca2+ of the wild type NaChBac (LESWAS) ion channel and its mutants (LASWAS and LEDWAS). (A) Representative whole cell current vs. time records obtained for channels in bath solution containing 140 mM Na+ (left) or 100 mM Ca2+ (right). (B) Current–voltage IV relationships (± SEM are shown as bars, n = 6 −12)) for LESWAS in Na+ solution (red squares) and Ca2+ solution (red triangles) and LEDWAS in Na+ solution (green squares) and Ca2+ solution (green triangles) normalized to the maximal peak Na+ current from the same cell. (C) Permeability Na+/Ca2+ ratios determined using reversal potentials, as described in [30], indicate that LEDWAS is a Ca2+ selective channel.

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.